| DOI | Resolve DOI: https://doi.org/10.1189/jlb.2RU0814-388R |
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| Author | Search for: Wang, Xiaofeng; Search for: Kulka, Marianna1 |
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| Affiliation | - National Research Council of Canada. National Institute for Nanotechnology
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| Format | Text, Article |
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| Subject | arachidonic acid; carboxypeptidase A; chymase; docosahexaenoic acid; docosapentaenoic acid; heparin; histamine; icosanoid; icosapentaenoic acid; interleukin 10; interleukin 13; interleukin 17; interleukin 1beta; interleukin 33; interleukin 4; interleukin 5; interleukin 6; interleukin 8; leukotriene B4; leukotriene C4; leukotriene D4; linolenic acid; major basic protein; omega 3 fatty acid; prostaglandin D2; prostaglandin E; serotonin; thrombocyte activating factor; tryptase; tumor necrosis factor; bone marrow derived mast cell; cell activation; cell adhesion; cell migration; cell viability; cytokine production; gene expression; inflammation; lipid raft; mast cell; mast cell degranulation; mediator release; phagocytosis; signal transduction |
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| Abstract | Mast cells are known to play a vital role in the development of inflammation in allergic responses. Recent studies have indicated that mast cell activation could be modulated by n-3 PUFAs, which have a wide range of well-documented health benefits. In our review, we summarize the recent findings and potential mechanisms of the effect of n-3 PUFAs on mast cell activation. This knowledge could provide new strategies for the development of therapeutic interventions for diseases mediated by mast cells. |
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| Publication date | 2015-05 |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| NPARC number | 21275622 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 14c05523-1e2f-4ac3-964a-824723df7e05 |
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| Record created | 2015-07-14 |
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| Record modified | 2020-04-22 |
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