Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1002/biot.201500176
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  1. National Research Council of Canada
FormatText, Article
SubjectBioreactors; Body fluids; DNA; Gene therapy; Mammals; Manufacture; Productivity; Viruses; Adeno-associated virus; Bioprocess optimization; HEK293T; ICELLis; Manufacturing strategy; Recombinant adeno-associated virus; Stirred tank bioreactors; Volumetric productivity; Vectors
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Peer reviewedYes
NPARC number21277505
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Record identifier155978b4-5776-493c-9910-871683b2cd98
Record created2016-03-09
Record modified2020-04-22
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