Abstract | Liposomes have application in serving as a support, or matrix, to form two dimensional crystals from those proteins which normally interact with the cytoplasmic membrane (Wingfield et al., 1979). This interaction includes membrane proteins that are largely embedded within the lipid bilayer, others with relatively more surface area exposed, and surface proteins which interact either via a single transmembrane strand or via a covalently linked lipid (Andreas et al., 1992). Recently, Andreas et al. demonstrated the two-dimensional crystallization of a solubilized surface protein from Comamonas acidovorans on lipid vesicles. |
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