Determination of polycyclic aromatic compounds by high-performance liquid chromatography with simultaneous mass spectrometry and ultraviolet diode array detection

DOI	Resolve DOI: https://doi.org/10.1093/chromsci/26.4.160
Author	Search for: Quilliam, M. A.¹; Search for: Sim, P. G.¹
Name affiliation	National Research Council Canada. NRC Institute for Marine Biosciences
Format	Text
Type	Article
Journal title	Journal of Chromatographic Science
ISSN	0021-9665 1945-239X
Volume	26
Issue	4
Pages	160–167
Abstract	A major problem in the determination of polycyclic aromatic compounds (PACs) in environmental samples is the extreme complexity of the extracts, even after extensive fractionation. The combination of high-performance liquid chromatography (HPLC) with simultaneous mass spectrometry (MS) and ultraviolet diode array detection (DAD) is a powerful tool for the identification and quantitation of such species with a high degree of confidence. HPLC allows the selective separation of a wide variety of PACs, including thermally labile and high molecular weight compounds. Electron ionization MS with the moving belt interface provides high sensitivity and selectivity, as well as structural information such as molecular weight, functional groups, and elemental composition. The diode array detector helps to differentiate isomeric structures and confirm compound identity.
Publication date	1988-04-01
Language	English
Peer reviewed	Yes
NPARC number	23001021
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Record identifier	1a4c03e4-48e4-46bf-8f72-66152387d874
Record created	2016-11-29
Record modified	2020-03-17