| DOI | Resolve DOI: https://doi.org/10.1016/j.carres.2019.107876 |
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| Author | Search for: Vinogradov, Evgeny1; Search for: Altman, Eleonora1 |
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| Affiliation | - National Research Council of Canada. Human Health Therapeutics
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| Format | Text, Article |
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| Subject | Fusobacterium necrophorum; capsular polysaccharide structure; peptidoglycan; N-acetylmuramic acid |
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| Abstract | A capsular polysaccharide (CPS) from Fusobacterium necrophorum subspecies necrophorum biotype A strain LA 81–617 was isolated from a saline cell wash and purified by gel and anion-exchange chromatography. The structure of the CPS was studied by one- and two-dimensional 1H and 13C NMR spectroscopy techniques in combination with electrospray ionization mass spectrometry (ESI-MS). The CPS was found to resemble the bacterial cell-wall murein polysaccharide backbone, consisting of N-acetylglucosamine and N-acetylmuramic acid (MurNAc) components, with the following structure:-[-4-β-MurNAc-4-β-GlcNAc-]n-with N-acetyl-1,6-anhydro-β-muramic acid at the reducing end. This is the first report on the structure of F. necrophorum capsular polysaccharide. |
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| Publication date | 2019-11-10 |
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| Publisher | Elsevier |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 1a583ded-9a29-48ce-89cc-5b67dcdb43d1 |
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| Record created | 2020-06-23 |
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| Record modified | 2020-06-29 |
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