| Download | - View accepted manuscript: Silicon-on-insulator guided mode resonance grating for evanescent field molecular sensing (PDF, 1.2 MiB)
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| DOI | Resolve DOI: https://doi.org/10.1364/OE.17.018371 |
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| Author | Search for: Schmid, J. H.1; Search for: Sinclair, W.1; Search for: García, J.; Search for: Janz, S.1; Search for: Lapointe, J.1; Search for: Poitras, D.1; Search for: Li, Y.2; Search for: Mischki, T.2; Search for: Lopinski, G.2; Search for: Cheben, P.1ORCID identifier: https://orcid.org/0000-0003-4232-9130; Search for: Delâge, A.1; Search for: Densmore, A.1; Search for: Waldron, P.1; Search for: Xu, D.-X.1 |
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| Affiliation | - National Research Council of Canada. NRC Institute for Microstructural Sciences
- National Research Council of Canada. NRC Steacie Institute for Molecular Sciences
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| Format | Text, Article |
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| Subject | silicon; molecular; monolayer; protein |
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| Abstract | We present experimental and theoretical results of label-free molecular sensing using the transverse magnetic mode of a 0.22 μm thick silicon slab waveguide with a surface grating implemented in a guided mode resonance configuration. Due to the strong overlap of the evanescent field of the waveguide mode with a molecular layer attached to the surface, these sensors exhibit high sensitivity, while their fabrication and packaging requirements are modest. Experimentally, we demonstrate a resonance wavelength shift of ~1 nm when a monolayer of the protein streptavidin is attached to the surface, in good agreement with calculations based on rigorous coupled wave analysis. In our current optical setup this shift corresponds to an estimated limit of detection of 0.2% of a monolayer of streptavidin. |
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| Publication date | 2009 |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| NPARC number | 16096610 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 1f071ff5-039e-4cac-9a60-afb32e1d9ecf |
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| Record created | 2010-09-27 |
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| Record modified | 2020-04-16 |
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