| Download | - View accepted manuscript: Stereoselective Diversity-Oriented Solution and Solid-Phase Synthesis of Tetrahydroquinoline-Based Polycyclic Derivatives (PDF, 730 KiB)
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| DOI | Resolve DOI: https://doi.org/10.1021/cc034053z |
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| Author | Search for: Arya, Prabhat1; Search for: Durieux, P.1; Search for: Chen, Z. -X1; Search for: Joseph, R.1; Search for: Leek, Donald1 |
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| Affiliation | - National Research Council Canada. NRC Steacie Institute for Molecular Sciences
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| Format | Text, Article |
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| Abstract | A diversity-oriented solution and solid-phase synthesis of tetrahydroquinoline-based tricyclic derivatives has been achieved from enantiomerically pure, natural product-like bicyclic scaffold. The solution synthesis of enantiopure bicyclic scaffold was developed by asymmetric hetero Michael reaction. Our approach for the synthesis of polycyclic derivatives utilized regio- and stereoselective hetero Michael reaction and ringclosing metathesis as key steps in solution and on solid phase. |
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| Publication date | 2004 |
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| In | |
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| Language | English |
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| NPARC number | 12340991 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 2328ce74-557c-41eb-a8b7-179efca0a9fc |
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| Record created | 2009-09-11 |
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| Record modified | 2020-04-17 |
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