| Download | - View accepted manuscript: Stereoselective Diversity-Oriented Solution and Solid-Phase Synthesis of Tetrahydroquinoline-Based Polycyclic Derivatives (PDF, 730 KiB)
|
|---|
| DOI | Resolve DOI: https://doi.org/10.1021/cc034053z |
|---|
| Author | Search for: Arya, Prabhat1; Search for: Durieux, P.1; Search for: Chen, Z. -X1; Search for: Joseph, R.1; Search for: Leek, Donald1 |
|---|
| Affiliation | - National Research Council of Canada. NRC Steacie Institute for Molecular Sciences
|
|---|
| Format | Text, Article |
|---|
| Abstract | A diversity-oriented solution and solid-phase synthesis of tetrahydroquinoline-based tricyclic derivatives has been achieved from enantiomerically pure, natural product-like bicyclic scaffold. The solution synthesis of enantiopure bicyclic scaffold was developed by asymmetric hetero Michael reaction. Our approach for the synthesis of polycyclic derivatives utilized regio- and stereoselective hetero Michael reaction and ringclosing metathesis as key steps in solution and on solid phase. |
|---|
| Publication date | 2004 |
|---|
| In | |
|---|
| Language | English |
|---|
| NPARC number | 12340991 |
|---|
| Export citation | Export as RIS |
|---|
| Report a correction | Report a correction (opens in a new tab) |
|---|
| Record identifier | 2328ce74-557c-41eb-a8b7-179efca0a9fc |
|---|
| Record created | 2009-09-11 |
|---|
| Record modified | 2020-04-17 |
|---|
