| DOI | Resolve DOI: https://doi.org/10.1039/c5cc04901f |
|---|
| Author | Search for: MacKenzie, D.A.1; Search for: Sherratt, A.R.1; Search for: Chigrinova, M.1; Search for: Kell, A.J.1; Search for: Pezacki, J.P.1 |
|---|
| Affiliation | - National Research Council of Canada. Medical Devices
|
|---|
| Format | Text, Article |
|---|
| Subject | carboxylic acid; dextro amino acid; dimethyl sulfoxide; macrogol; nitrone derivative; vancomycin; bacterial cell wall; cycloaddition; Escherichia coli; fluorescence microscopy; Gram bacterium; Lactococcus lactis; Listeria innocua; protein structure |
|---|
| Abstract | Unnatural D-amino acids bearing endocyclic nitrones were developed for live-cell labelling of the bacterial peptidoglycan layer. Metabolic incorporation of D-Lys and D-Ala derivatives bearing different endocyclic nitrones was observed in E. coli, L. innocua, and L. lactis. The incorporated nitrones of these bacteria then rapidly underwent strain-promoted alkyne-nitrone cycloaddition (SPANC) reactions affording chemically modified bacteria. |
|---|
| Publication date | 2015 |
|---|
| In | |
|---|
| Language | English |
|---|
| Peer reviewed | Yes |
|---|
| NPARC number | 21276975 |
|---|
| Export citation | Export as RIS |
|---|
| Report a correction | Report a correction (opens in a new tab) |
|---|
| Record identifier | 2fa82a67-711e-4927-bf2c-52e6a835fcdd |
|---|
| Record created | 2015-11-10 |
|---|
| Record modified | 2022-11-18 |
|---|
