| Author | Search for: Kogan, G.; Search for: Brisson, J.; Search for: Kasper, D.; Search for: Von Hunolstein, C.; Search for: Orefici, G.; Search for: Jennings, Harold |
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| Format | Text, Article |
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| Subject | 13C; 13C-NMR; 1D; 1H; 2D; Acetylglucosamine; acid; bacterial; bacterial capsules; Canada; capsular polysaccharide; capsule; carbohydrate conformation; carbohydrate sequence; chemistry; d-glucose; elucidation; galactose; glucose; group B streptococcus; group-B; high-resolution; magnetic resonance spectroscopy; molar; molecular sequence data; N-acetylneuraminic acid; NMR; NMR spectroscopy; polysaccharide; repeating unit; repetitive sequences, nucleic acid; resolution; resolution NMR spectroscopy; sialic; sialic acids; spectroscopy; strain; streptococcus; streptococcus agalactiae; structural elucidation; unit |
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| Abstract | The type VII capsular polysaccharide isolated from the newly discovered group B Streptococcus (GBS) strain contains D-glucose, D-galactose, N-acetyl-D-glucosamine and N-acetylneuraminic acid in the molar ratio 2:2:1:1. High-resolution one- and two-dimensional (1D and 2D) 1H and 13C NMR spectroscopy of the native and desialylated polysaccharides showed the type VII GBS capsular polysaccharide to contain the following branched hexasaccharide repeating unit: [formula: see text] Despite extensive structural similarity with the previously described GBS polysaccharides, the type VII polysaccharide showed no cross-reaction with the heterologous antisera |
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| Publication date | 1995-11-07 |
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| In | |
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| Language | English |
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| NRC number | KOGAN1995 |
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| NPARC number | 9361350 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 43d22159-9357-4aab-9495-dc7186dd1b10 |
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| Record created | 2009-07-10 |
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| Record modified | 2020-04-29 |
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