| Author | Search for: Constabel, F.1; Search for: Kurz, W. G. W.1; Search for: Kartha, K. K.1; Search for: Kutney, J. P. |
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| Affiliation | - National Research Council of Canada. Prairie Regional Laboratory
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| Format | Text, Article |
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| Conference | The First International Symposium on the Life Sciences: Biotransformation by Cultured Cells, October 4-7, 1982, Japan |
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| Abstract | The objective of our research is the isolation and preservation of cell lines with accumulate bisindole alkaloids with anti-leukemic activity, i.e. vincristine and vinblastine or their monomeric moieties catharanthine and vindoline. Our strategy required to first initiate a large number serial callus cultures from as many donor plants, to screen this material for cell cultures (line) with desirable alkaloid profiles, to then design a selection system for vinblastine or vincristine cell, and finally to devise a protocol for cryopreservation of such cells. |
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| Publication date | 1982-10-04 |
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| Publisher | Toyoba Co., Ltd |
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| In | |
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| Language | English |
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| Peer reviewed | No |
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| NRC number | NRCC 20413 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 538c1dee-0e50-49dc-9bee-3432766599ba |
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| Record created | 2024-04-17 |
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| Record modified | 2024-04-22 |
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