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Nitric oxide inhibitory activity of monogalactosylmonoacylglycerols from a freshwater microalgae Chlorella sorokiniana

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1080/14786419.2012.696255
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Affiliation
  1. National Research Council of Canada. Aquatic and Crop Resource Development
FormatText, Article
Subjectmonogalactosylmonoacylglycerol; nitric oxide; Chlorella sorokiniana; microalgae
Abstract
Chemical investigation of the freshwater microalgae Chlorella sorokiniana led to the isolation of a new monogalactosylmonoacylglycerol, namely, (2S)-1-O-(7Z,10Z-hexadecadienoyl)-3-O-β-D-galactopyranosylglycerol (1) together with a known glycolipid (2S)-1-O-(7Z,10Z,13Z-hexadecatrienoyl)-3-O-β-D-galactopyranosylglycerol (2). Both monogalactosylmonoacylglycerols showed dose-dependent nitric oxide (NO) inhibitory activity against lipopolysaccharide-induced NO production in RAW264.7 macrophage cells suggesting their possible use as anti-inflammatory agents.
Publication date
In
  • Natural Product Research 27, no. 11 (18 June 2012): 1028–1031.
LanguageEnglish
Peer reviewedYes
NRC numberNRCC 54065
NPARC number21268613
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Record identifier593afa4e-0433-4387-bbaf-45a99fcccca0
Record created2013-10-28
Record modified2020-04-21
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