| Author | Search for: Van Dooren, Tom; Search for: Merchiers, P.; Search for: Borghgraef, P.; Search for: Dewachter, I.; Search for: Van der Auwera, I.; Search for: Wera, S.; Search for: Lauwereys, M.; Search for: Roland, B.; Search for: Abulrob, A.1; Search for: Stanimirovic, D.1; Search for: Hoogenboom, H.; Search for: de Haard, H.; Search for: Van Leuven, F. |
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| Affiliation | - National Research Council of Canada. NRC Institute for Biological Sciences
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| Format | Text, Other |
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| Subject | Alzheimer's disease; amyloid peptides; Nanobodies |
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| Abstract | The lack of early objective diagnosis and disease modifying therapy remains the major medical problem in Alzheimer's disease (AD). The promise of different active and passive immunization strategies that are targeting the amyloid peptides must be explored as wide as possible. Here we report for the first time a biochemical and immuno-histochemical characterization and validation of "Nanobodies TM" directed against amyloid peptides. Nanobodies are therapeutic proteins derived from so-called heavy chain antibodies in the Camelidae that are experimentally derived from llamas. |
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| Language | English |
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| Peer reviewed | Yes |
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| NPARC number | 21275184 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 613270c1-1ae3-4fe7-8b4e-113fa3a7a9cb |
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| Record created | 2015-05-22 |
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| Record modified | 2020-03-03 |
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