| DOI | Resolve DOI: https://doi.org/10.1016/0925-4439(94)00056-V |
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| Author | Search for: Jackson, Michael1; Search for: Choo, Lin-P'ing1; Search for: Watson, Peter H.; Search for: Halliday, William C.; Search for: Mantsch, Henry H.1 |
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| Affiliation | - National Research Council of Canada. NRC Institute for Biodiagnostics
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| Format | Text, Article |
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| Subject | Human tissue; MR; Collagen; Connective tissue; Cancer |
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| Abstract | Infrared spectra of human central nervous system tissue and human breast carcinoma are presented. The spectra are discussed in terms of the composition of the tissues. It is shown that differences between spectra of white and grey matter can be rationalised on the basis of differences in lipid content. Spectra of the choroid plexus and arachnoid villus of the meninges show a series of absorptions not observed in other CNS tissue. These absorptions are discussed in terms of the connective tissue content of the samples. We demonstrate that the presence of collagen results in the appearance of a series of characteristic absorptions which may be mis-assigned as DNA phosphate absorptions. The implications of the presence of collagen in tissues for the diagnosis of disease states by IR spectroscopic methods, with particular reference to cancer, is discussed. |
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| Publication date | 1995-01-25 |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| NRC number | NRC-IBD-302 |
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| NPARC number | 9742654 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 62be885b-b19a-4190-b433-d9ab5ddce9e1 |
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| Record created | 2009-07-17 |
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| Record modified | 2020-04-29 |
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