Constituents of Chinese propolis and their antiproliferative activities

DOI	Resolve DOI: https://doi.org/10.1021/np010486c
Author	Search for: Usia, Tepy; Search for: Banskota, Arjun H.; Search for: Tezuka, Yasuhiro; Search for: Midorikawa, Kiyoshi; Search for: Matsushige, Katsumichi; Search for: Kadota, Shigetoshi
Format	Text, Article
Abstract	Two new flavonoids, 3-O-[(S)-2-methylbutyroyl]pinobanksin (1) and 6-cinnamylchrysin (2), were isolated from the EtOAc-soluble fraction of the MeOH extract of Chinese propolis, along with 12 known compounds (3−14). The structures of the isolated compounds were elucidated on the basis of spectroscopic and chemical analyses. The isolated compounds were tested for their antiproliferative activity toward five different cancer cell lines. Benzyl caffeate (13) and phenethyl caffeate (14) showed potent antiproliferative activity toward tested cell lines with a selective activity toward colon 26-L5 carcinoma cell line (EC50 values: 13, 1.01; 14, 0.30 μM).
Publication date	2002-04-18
In	Journal of Natural Products 65, no. 5 (18 April 2002): 673–676.
Language	English
Peer reviewed	Yes
NRC publication	This is a non-NRC publication "Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.
NPARC number	21274779
Export citation	Export as RIS
Report a correction	Report a correction (opens in a new tab)
Record identifier	664325a7-2712-4e90-8a44-56ea806d5892
Record created	2015-04-08
Record modified	2020-03-30