| Abstract | Alzheimer's disease (AD) is the most prevalent neurodegenerative disease worldwide. Currently, AD diagnosis is based on a multidimensional approach that involves clinical, neuropathological examination and evaluation of biomarkers. The burden of AD is further exacerbated by the fact that brain damage actually begins to develop several years before the diagnosis or even mild cognitive impairment (MCI) is observed (Long and Holtzman, 2019). Therefore, developing early and accurate diagnostic methods is urgently needed. The present Research Topic aims to highlight the latest experimental techniques and methods used to investigate fundamental questions in Alzheimer's disease and related dementias, from integrative functions to molecular and potential therapeutics. |
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