| DOI | Resolve DOI: https://doi.org/10.1088/1742-6596/351/1/012011 |
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| Author | Search for: Uhríková, D.; Search for: Kučerka, N.1; Search for: Lengyel, A.; Search for: Pullmannová, P.; Search for: Teixeira, J.; Search for: Murugova, T.; Search for: Funari, S. S.; Search for: Balgavý, P. |
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| Affiliation | - National Research Council of Canada. NRC Canadian Neutron Beam Centre
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| Format | Text, Article |
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| Abstract | The structure of aggregates formed due to DNA interaction with dipalmitoylphosphatidylcholine (DPPC) in presence of Ca2+ and Zn2+ is examined using small-angle synchrotron X-ray diffraction (SAXD) and small-angle neutron scattering (SANS). SAXD detected two structures: LC - condensed lamellar phase and LX - lamellar phase with DNA strands intercalated between the adjacent lipid bilayers, without regular packing at low cation concentration (~1 mM). The high concentration of Zn2+ induces a macroscopic phase separation in mixtures. The SANS curves of DPPC+ions2+ vesicles evaluated using the strip function model have shown different modes of cations binding to the DPPC bilayers. |
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| Publication date | 2012 |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| NPARC number | 21268039 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 6ed13fbc-d0a4-4610-be4c-ca196d807514 |
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| Record created | 2013-04-04 |
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| Record modified | 2020-04-21 |
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