| DOI | Resolve DOI: https://doi.org/10.3109/10731199.2011.560120 |
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| Author | Search for: Afkhami, Fatemeh; Search for: Durocher, Yves1; Search for: Prakash, Satya |
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| Affiliation | - National Research Council of Canada. NRC Biotechnology Research Institute
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| Format | Text, Article |
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| Subject | artificial cell; microcapsule; co-encapsulation; angiogenesis; IFNα; VEGF165b; alginate; poly-L-lysine; cell therapy |
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| Abstract | Targeted and simultaneous delivery VEGF165b and IFN alpha in anti-angiogenic and other applications could offer several advantages. For this a system was design using artificial cell alginate-poly-L-lysine- alginate (APA) microcapsules. Result confirms the ability of this system for simultaneous production of these proteins for 28-days. The IFN alpha on a 3 days period increased from 8 ± 0.36 μg/ml at day 10 to 27 ± 2.4 μg/ml at day 16 and then dropped to 6.5 ± 0.5 μg/ml. The VEGF165b on a 3 days period increased from 2.7 ± 0.7 μg/ml at day 10 to 6.9 ± 1 μg/ml at day 16. |
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| Publication date | 2012-02 |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| NRC number | NRCC 53203 |
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| NPARC number | 21268296 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 77acc44e-2dce-4e5e-a1a9-7df93a98f5a1 |
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| Record created | 2013-06-17 |
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| Record modified | 2020-04-21 |
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