Enzyme reactions in the presence of cyclodextrins : biosensors and enzyme assays

DOI	Resolve DOI: https://doi.org/10.1016/S0167-7799(00)89002-2
Author	Search for: Luong, John H. T.¹; Search for: Brown, R. Stephen¹; Search for: Male, Keith B.¹; Search for: Cattaneo, Maurice V.¹; Search for: Zhao, Shishan¹
Name affiliation	National Research Council of Canada. NRC Biotechnology Research Institute
Format	Text, Article
Abstract	Cyclodextrins, macrocyclic carbohydrates with apolar internal cavities, can form complexes with, and solubilize many normally water-insoluble compounds. Ferrocene and its derivaties, tetrathiafulvalene and tetramethylbenzidine, can function as redox mediators, but are insoluble in water; when they are complexed with cyclodextrins, they can be used in enzymatic assays and in the construction of mediated biosensors. In addition, the solubilization of polynuclear aromatic hydrocarbons (PAHs), including the potent carcinogen benzo[a]pyrene, by cyclodextrins has enabled the detection of these important environmental contaminants.
Publication date	1995-11
In	Trends in Biotechnology 13, no. 11 (November 1995): 457–463.
Language	English
NRC number	34503
NPARC number	3540145
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Record identifier	7c74bfcf-51c3-4c8d-9b2e-455eb1f6b487
Record created	2009-03-01
Record modified	2020-04-29