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| DOI | Resolve DOI: https://doi.org/10.1007/s00216-022-04292-0 |
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| Author | Search for: Le, Phuong Mai1ORCID identifier: https://orcid.org/0000-0002-6101-5252; Search for: Martineau, Estelle; Search for: Akoka, Serge; Search for: Remaud, Gerald; Search for: Chartrand, Michelle M. G.1ORCID identifier: https://orcid.org/0000-0002-2377-2615; Search for: Meija, Juris1ORCID identifier: https://orcid.org/0000-0002-3349-5535; Search for: Mester, Zoltán1ORCID identifier: https://orcid.org/0000-0002-2377-2615 |
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| Affiliation | - National Research Council Canada. Metrology Research Centre
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| Format | Text, Article |
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| Subject | site specific isotope ratios; carbon; ¹³C-qNMR; vanillin; certified reference material |
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| Abstract | Vanillin, one of the world’s most popular flavor used in food and pharmaceutical industries, is extracted from vanilla beans or obtained (bio)-synthetically. The price of natural vanillin is considerably higher than that of its synthetic alternative which leads increasingly to counterfeit vanillin. Here, we describe the workflow of combining carbon isotope ratio combustion mass spectrometry with quantitative carbon nuclear magnetic resonance spectrometry (¹³C-qNMR) to obtain carbon isotope measurements traceable to the Vienna Peedee Belemnite (VPDB) with 0.7‰ combined standard uncertainty (or expanded uncertainty of 1.4‰ at 95% confidence level). We perform these measurements on qualified Bruker 400 MHz instruments to certify site-specific carbon isotope delta values in two vanillin materials, VANA-1 and VANB-1, believed to be the first intramolecular isotopic certified reference material (CRMs). Graphical abstract |
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| Publication date | 2022-09-13 |
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| Publisher | Springer |
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| Licence | |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | 851a8ba4-13ff-4137-90e5-4b30d23f5a99 |
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| Record created | 2023-01-06 |
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| Record modified | 2023-01-06 |
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