National Research Council of Canada. NRC Institute for Marine Biosciences
Text, Book Chapter
The 10th International IUPAC Symposium on Mycotoxins and Phycotoxins, May 21-25, 2000 Guaruja, Brazil
phycotoxins; shellfish poisoning; liquid chromatography; mass spectrometry
The combination of liquid chromatography and mass spectrometry LC-MS) is a powerful tool for the detection and quantitation of phycotoxins in plankton and shellfish at trace levels, the identification of new toxins, the investigation of toxin production by plankton, and the study of toxin metabolism in shellfish. Progress in development of LC-MS as a “universal” toxin analysis method for the comprehensive analysis of a wide range of toxins is now described. Two basic methods have been developed: lipophilic toxins are separated on a reversed phase column using gradient elution, while the paralytic shellfish poisoning (PSP) toxins are separated on a hydrophilic interaction LC column using isocratic elution.
Wageningen de Koe
Mycotoxins and Phycotoxins in Perspective at the Turn of the Millenium: Proceedings of 10th International IUPAC Symposium on Mycotoxins and Phycotoxins, 21-25 May, 2000 Guaruja (Brazil): 383–391.