| Download | - View accepted manuscript: Development of a MRI phantom to emulate the relaxation times of the neonatal brain at 3 Tesla (PDF, 540 KiB)
|
|---|
| Author | Search for: Orr, T.N.; Search for: Gelman, N.; Search for: Winter, J.; Search for: Campbell, G.1; Search for: Thompson, R.T. |
|---|
| Affiliation | - National Research Council of Canada. NRC Industrial Materials Institute
|
|---|
| Format | Text, Article |
|---|
| Conference | 15th Scientific Meeting and Exhibition, International Society for Magnetic Resonance in Medicine, May 19-25, Berlin Germany |
|---|
| Abstract | Prematurity greatly increases the risk of neurological impairment in newborn infants. Magnetic resonance imaging (MRI) provides powerful techniques for non-invasively investigating the impact of premature birth on early brain development. Experimental testing of MRI techniques on human nenonates is not ethically appropriate. Our previous work has shown that techniques used for brain imaging in adults are not optimal for neonates. Therefore, there is a crucial need for phantoms that can mimic MRI properties of the neonatal brain. Polyvinyl alcohol cryogel (PVA-C) has been investigated as a MRI phantom material for the adult brain. Our previous work showed that MRI relaxation times (T1 and T2) of 6-15% PVA-C were lower than those reported for neonatal white matter at 2.30 Tesla. The objective of this study was to investigate the relationship between PVA-C relation times and temperature to determine if sufficiently long relaxation times could be obtained by increasing temperature. |
|---|
| Publication date | 2007 |
|---|
| In | |
|---|
| Language | English |
|---|
| Peer reviewed | Yes |
|---|
| NPARC number | 21274310 |
|---|
| Export citation | Export as RIS |
|---|
| Report a correction | Report a correction (opens in a new tab) |
|---|
| Record identifier | 96c53db6-bff3-4389-8739-25f797943f2d |
|---|
| Record created | 2015-03-09 |
|---|
| Record modified | 2020-06-04 |
|---|
