| Download | - View final version: Dedicated industrial oilseed crops as metabolic engineering platforms for sustainable industrial feedstock production (PDF, 1.4 MiB)
|
|---|
| DOI | Resolve DOI: https://doi.org/10.1038/srep22181 |
|---|
| Author | Search for: Zhu, Li-Hua; Search for: Krens, Frans; Search for: Smith, Mark A.1; Search for: Li, Xueyuan; Search for: Qi, Weicong; Search for: van Loo, Eibertus N.; Search for: Iven, Tim; Search for: Feussner, Ivo; Search for: Nazarenus, Tara J.; Search for: Huai, Dongxin; Search for: Taylor, David C.1; Search for: Zhou, Xue-Rong; Search for: Green, Allan G.; Search for: Shockey, Jay; Search for: Klasson, K. Thomas; Search for: Mullen, Robert T.; Search for: Huang, Bangquan; Search for: Dyer, John M.; Search for: Cahoon, Edgar B. |
|---|
| Affiliation | - National Research Council of Canada. Aquatic and Crop Resource Development
|
|---|
| Format | Text, Article |
|---|
| Subject | Biochemistry; Molecular engineering plants |
|---|
| Abstract | Feedstocks for industrial applications ranging from polymers to lubricants are largely derived from petroleum, a non-renewable resource. Vegetable oils with fatty acid structures and storage forms tailored for specific industrial uses offer renewable and potentially sustainable sources of petrochemical-type functionalities. A wide array of industrial vegetable oils can be generated through biotechnology, but will likely require non-commodity oilseed platforms dedicated to specialty oil production for commercial acceptance. Here we show the feasibility of three Brassicaceae oilseeds crambe, camelina, and carinata, none of which are widely cultivated for food use, as hosts for complex metabolic engineering of wax esters for lubricant applications. Lines producing wax esters >20% of total seed oil were generated for each crop and further improved for high temperature oxidative stability by down-regulation of fatty acid polyunsaturation. Field cultivation of optimized wax ester-producing crambe demonstrated commercial utility of these engineered crops and a path for sustainable production of other industrial oils in dedicated specialty oilseeds. |
|---|
| Publication date | 2016-02-26 |
|---|
| Publisher | Nature Publishing Group |
|---|
| In | |
|---|
| Language | English |
|---|
| Peer reviewed | Yes |
|---|
| Identifier | srep22181 |
|---|
| NPARC number | 23000130 |
|---|
| Export citation | Export as RIS |
|---|
| Report a correction | Report a correction (opens in a new tab) |
|---|
| Record identifier | 9a04820c-79df-4d14-8cb3-44d371fad44d |
|---|
| Record created | 2016-06-06 |
|---|
| Record modified | 2020-06-02 |
|---|
