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Buoyancy-driven step emulsification on pneumatic centrifugal microfluidic platforms

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1039/D0LC00333F
AuthorSearch for: 1ORCID identifier: https://orcid.org/0000-0002-1786-0803; Search for: 1ORCID identifier: https://orcid.org/0000-0001-8594-9191; Search for: ; Search for: 1; Search for: 1ORCID identifier: https://orcid.org/0000-0002-8838-5528; Search for: 1
Affiliation
  1. National Research Council Canada. Medical Devices
FormatText, Article
Abstract
We present here a new method for controlling the droplet size in step emulsification processes on a centrifugal microfluidic platform, which, in addition to the centrifugal force, uses pneumatic actuation for fluid displacement. We highlight the importance of the interplay between buoyancy effects and the flow rate at the step junction, and provide a simple analytical model relating these two quantities to the size of the droplets. Numerical models as well as experiments with water-in-oil emulsions are performed in support of the proposed model.
Publication date
PublisherRoyal Society of Chemistry
In
  • Lab on a Chip 20, no. 17 (7 September 2020): 3091–3095.
LanguageEnglish
Peer reviewedYes
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Record identifier9a1fd940-8084-41f4-b7b9-dcaa41e4e771
Record created2022-01-07
Record modified2022-01-07
Date modified: