The structure of the Escherichia coli O148 lipopolysaccharide core region and its linkage to the O-specific polysaccahride

DOI	Resolve DOI: https://doi.org/10.1016/j.carres.2010.10.012
Author	Search for: Kubler-Kielb, Joanna; Search for: Lai, Wen-Tzu; Search for: Schneerson, Rachel; Search for: Vinogradov, Evgeny¹
Affiliation	National Research Council of Canada. NRC Institute for Biological Sciences
Format	Text, Article
Subject	LPS; O-specific polysaccharide; core; structure; Escherichia coli O148
Abstract	Recently it was demonstrated that Shigella dysenteriae type 1, a cause of severe dysentery epidemics, gained its O-specific polysaccharide (O-SP) from Escherichia coli O148. The O-SPs of these bacteria differ only by a galactose residue in the repeat unit of S. dysenteriae type 1 in place of a glucose residue in E. coli O148. Herein, we analyzed the core structure and its linkage to the O-SP in E. coli O148 LPS. Both were found to be identical to those of S. dysenteriae type 1 structures, further supporting the relatedness of these two bacteria. The following structure of the core with one repeat unit of the O-SP has been assigned (all have D-configuration except L-Rha):
Publication date	2011-01-01
In	Carbohydrate Research 346 (1 January 2011): 150–152.
Language	English
Peer reviewed	Yes
NPARC number	17652993
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Record identifier	9d72ca6b-14ac-4060-831d-d1422a7a9137
Record created	2011-04-01
Record modified	2022-11-18