| DOI | Resolve DOI: https://doi.org/10.1117/12.778936 |
|---|
| Author | Search for: Xu, Dan-Xia; Search for: Post, Edith1; Search for: Densmore, Adam1; Search for: Waldron, Philip1; Search for: Janz, Siegfried1; Search for: Lopinski, G.2; Search for: Mischki, T.2; Search for: Cheben, Pavel1ORCID identifier: https://orcid.org/0000-0003-4232-9130; Search for: Lapointe, Jean; Search for: Delâge, André1; Search for: Lamontagne, Boris1; Search for: Schmid, Jens H.1 |
|---|
| Affiliation | - National Research Council of Canada. NRC Institute for Microstructural Sciences
- National Research Council of Canada. NRC Steacie Institute for Molecular Sciences
|
|---|
| Format | Text, Article |
|---|
| Conference | Photonics North 2007, June 3-7, 2007, Ottawa, Ontario, Canada |
|---|
| Abstract | We exploit the unique properties of the silicon-on-insulator material platform to demonstrate a new series of planar waveguide evanescent field sensors for biological / chemical sensing. These sensors, combined with state-of-the-art surface functionalization chemistries, offer a sensitive, label-free means for the specific detection of biomolecules, without the need for fluorescent tags employed in conventional fluorescence-based biochips. The use of silicon photonic wire waveguide technology allows sensors with extremely small footprint and small radius of curvature to be fabricated, facilitating the development of densely packed sensor arrays for multi-parameter analysis, particularly attractive for drug discovery, pathogen detection, genomics and disease diagnostics. We show that high index contrast silicon photonic wire waveguides not only provide the above stated advantages but also offer increased sensitivity over that of evanescent field sensors constructed on other common waveguide material platforms. This results from the unique properties of the optical modes of silicon photonic wire waveguides, which exhibit very large surface electric field magnitude and strong localization near the waveguide surface. We discuss the design and fabrication of silicon-on-insulator-based Mach-Zehnder interferometer sensors and experimentally demonstrate their performance to detect bulk solution refractive index change and to monitor the specific adsorption of streptavidin to biotinylated waveguides. |
|---|
| Publication date | 2007-10-26 |
|---|
| Publisher | SPIE |
|---|
| In | |
|---|
| Series | |
|---|
| Language | English |
|---|
| Peer reviewed | Yes |
|---|
| NPARC number | 9373350 |
|---|
| Export citation | Export as RIS |
|---|
| Report a correction | Report a correction (opens in a new tab) |
|---|
| Record identifier | a8e0920d-c65d-4153-a62c-7e60ec071b2b |
|---|
| Record created | 2009-07-10 |
|---|
| Record modified | 2020-05-10 |
|---|
