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2,3-Dimethoxy-5-methyl-1,4-benzoquinones and 2-methyl-1,4-naphthoquinones: glycation inhibitors with lipid peroxidation activity

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1016/j.bmcl.2004.12.029
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Affiliation
  1. National Research Council of Canada. NRC Biotechnology Research Institute
FormatText, Article
Subjectglycation; pharmaceutical
Abstract
Anti-glycation activity of our anti-oxidant quinone library was measured and several 2,3-dimethoxy-5-methyl-1,4-benzoquinones and 2-methyl-1,4-naphthoquinones were identified as novel inhibitors of glycation, of which 2,3-dimethoxy-5-methyl-1,4-benzoquinones 13b is the most potent glycation inhibitor with around 50 [mu]M of the IC50 value
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NRC number47502
NPARC number3538814
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Record identifiera976760e-4912-4e0b-aa2c-831642f0c955
Record created2009-03-01
Record modified2020-04-07
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