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Characterization of biopharmaceuticals by NMR spectroscopy

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1016/j.trac.2013.03.009
AuthorSearch for: 1
Affiliation
  1. National Research Council of Canada. Security and Disruptive Technologies
FormatText, Article
SubjectBiopharmaceuticals; Biosimilar; Characterization; Formulation; Nuclear magnetic resonance (NMR); Oligonucleotide; Peptide; Polysaccharide; Protein; Quality control
Abstract
Recent improvements in nuclear magnetic resonance (NMR) - automation, sensitivity, resolution, pulse-sequence design and spectral processing - are giving novel insights into a wide range of biotech drugs. Real-world applications and emerging trends in biopharmaceutical NMR are being used to help in discovery, design, and characterization of these drugs and to improve assessment of their efficacy, quality and similarity. © 2013 Elsevier Ltd.
Publication date
In
  • TrAC - Trends in Analytical Chemistry 48 (2013): 96–111.
LanguageEnglish
Peer reviewedYes
NPARC number21271872
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Record identifierac6f3f47-5e19-4da1-87d0-dc81b744d01c
Record created2014-04-24
Record modified2020-04-22
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