| DOI | Resolve DOI: https://doi.org/10.1016/j.it.2018.09.008 |
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| Author | Search for: Brooks, Cory L.; Search for: Rossotti, Martin A.1; Search for: Henry, Kevin A.1 |
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| Affiliation | - National Research Council of Canada. Human Health Therapeutics
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| Format | Text, Article |
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| Subject | heavy chain-only antibody; single-domain antibody; VHHVNAR; comparative immunology; evolutionary immunology |
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| Abstract | Homodimeric antibodies devoid of light chains have evolved multiple times through convergent evolution, yet their specific immunological functions remain poorly understood. We survey the molecular and structural features of these antibodies, their immunological functions in host defense, and reflect on the long-standing question of the evolutionary forces driving their emergence. |
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| Publication date | 2018-10-10 |
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| Publisher | Elsevier |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | ae43c3de-0ebc-4c54-9c26-d061060614ae |
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| Record created | 2019-04-17 |
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| Record modified | 2020-03-16 |
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