National Research Council of Canada. NRC Institute for Biological Sciences
UDP-hexos-4-ulose sugars occupy a central role in the biosynthesis of lipopolysaccharides, capsular polysaccharides, and antibiotics in bacteria. Little is known about these sugars as they are labile compounds that are produced in minute quantities within the bacterial cell. Examination of the PglF, PseB, WbjB, and WbjC reactions directly with NMR lead to the first detailed structural description of UDP-hexos-4-ulose sugars in various bacteria.