The relationship between the serogroup antigen and lipopolysaccharide of Legionella pneumophila

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DOI	Resolve DOI: https://doi.org/10.1017/S0022172400062513
Author	Search for: Conlan, J. W.; Search for: Ashworth, L. A. E.
Format	Text, Article
Subject	antibodies, bacterial/analysis; antigens, bacterial/analysis; electrophoresis, polyacrylamide gel; enzyme-linked immunosorbent assay; legionella/classification; legionella/immunology; legionella/isolation & purification; lipopolysaccharides/analysis; serotyping; species specificity
Abstract	Serogroup-specific antigen was extracted from a number of Legionella pneumophila strains and compared with phenol-water extracted lipopolysaccharide on the basis of gel filtration, chemical analysis, SDS-PAGE and reaction with serogroup-specific antibody in immunoblots. Serogroup specificity is apparently borne by the O side-chains of the lipopolysaccharide, which, although smooth in type, partitions in the phenol phase. For four serogroup 1 strains tested, there was no qualitative correlation between O side-chain length and pulmonary virulence for guinea-pigs.
Publication date	1986-02
Publisher	Cambridge University Press
In	The Journal of Hygiene 96, no. 1: 39–48.
Language	English
Peer reviewed	Yes
NRC publication	This is a non-NRC publication "Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.
NRC number	CONLAN1986
NPARC number	9382845
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Record identifier	b8039567-d7de-4729-8200-56c70357d9d3
Record created	2009-07-10
Record modified	2020-05-27

Date modified:: 2024-07-01