| Download | - View accepted manuscript: Combinatorial chemistry toward understanding the function(s) of carbohydrates and carbohydrate conjugates (PDF, 691 KiB)
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| DOI | Resolve DOI: https://doi.org/10.1002/1521-3765(20010202)7:3<555::AID-CHEM555>3.0.CO;2-I |
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| Author | Search for: Barkley, Angela1; Search for: Arya, Prabhat1 |
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| Affiliation | - National Research Council of Canada. NRC Steacie Institute for Molecular Sciences
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| Format | Text, Article |
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| Subject | Artificial glycopeptides; carbohydrates; combinatorial chemistry; glycoconjugates; glycomimetics |
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| Abstract | Combinatorial chemistry has contributed significantly to understanding the structure - function relationships of biologically important molecules such as proteins and nucleic acids. However, carbohydrates and carbohydrate conjugates, which have been identified as key modulators of several biological functions have not enjoyed the same measure of success. The complexity and synthetic challenges of carbohydrate conjugates have resulted in a number of conceptual approaches to rapidly access sufficient quantities of these biomolecules. This article summarizes these combinatorial approaches and also highlights fully automated library synthesis of artificial glycopeptides with the goals of understanding their biological roles. |
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| Publication date | 2001-01-26 |
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| In | |
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| Language | English |
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| NPARC number | 12341013 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | bdf018ee-e609-4303-91f6-89b042438edf |
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| Record created | 2009-09-11 |
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| Record modified | 2020-03-27 |
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