Development of an anti-vascular cell adhesion protein-1 aptamer for molecular imaging and inflammation detection in transgenic mouse model of Alzheimer's disease

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1166/jbn.2015.2154
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Name affiliation
  1. National Research Council Canada. Human Health Therapeutics
FormatText
TypeArticle
Journal titleJournal of Biomedical Nanotechnology
ISSN1550-7033
Volume11
Issue12
Pages22642274; # of pages: 11
Subjectcell adhesion; cell; cytology; diagnosis; dissociation; endothelial cells; infrared devices; mammals; molecules; neurodegenerative diseases; pathology; Alzheimer's disease; aptamers; near-infrared fluorescence imaging; therapeutic monitoring; vascular cell adhesion; vcam-1; molecular imaging; amyloid beta protein; aptamer; cyanine dye 5 11R6; fluorescein; fluorescent dye; single stranded DNA; vascular cell adhesion molecule 1; animal experiment; animal model; animal tissue; cerebellum; DNA library; DNA sequence; electrophoretic mobility; fluorescence imaging; fluorescence microscopy; gel mobility shift assay; human cell; in vitro selection; In vivo study; mouse; nervous system inflammation; protein targeting; umbilical vein endothelial cell; disease model; fluorescence imaging; genetics; inflammation; metabolism; molecular imaging; nucleotide sequence; transgenic mouse; aptamers, nucleotide; base sequence; disease models, animal; human umbilical vein endothelial cells; inflammation; mice, transgenic; optical imaging
Abstract
Publication date
PublisherAmerican Scientific Publishers
LanguageEnglish
Peer reviewedYes
NPARC number21277338
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Record created2016-03-09
Record modified2019-08-28
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