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Cytotoxic cycloartane-type triterpenes from Combretum quadrangulare

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1016/S0960-894X(98)00644-1
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FormatText, Article
Abstract
Seven novel cycloartane-type triterpenes were isolated from Combretum quadrangulare, and their structures were elucidated on the basis of spectral analysis. All these compounds were tested for their cytotoxicity against murine colon 26-L5 carcinoma cells. Methyl quadrangularate B (2) and methyl quadrangularate D (4) exhibited potent cytotoxicity having ED50 values 9.54 and 5.42 μM, respectively.
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In
  • Bioorganic and Medicinal Chemistry Letters 8, no. 24 (15 December 1998): 3519–3524.
LanguageEnglish
Peer reviewedYes
NRC publication
This is a non-NRC publication

"Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.

NPARC number21275307
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