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Concentration-independent spontaneously forming biomimetric vesicles

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1103/PhysRevLett.91.158105
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Affiliation
  1. National Research Council of Canada. NRC Canadian Neutron Beam Centre
FormatText, Article
Abstract
In this Letter we present small-angle neutron scattering data from a biomimetic system composed of the phospholipids dimyristoyl and dihexanoyl phosphorylcholine (DMPC and DHPC, respectively). Doping DMPC-DHPC multilamellar vesicles with either the negatively charged lipid dimyristoyl phosphorylglycerol (DMPG, net charge -1) or the divalent cation, calcium (Ca2+), leads to the spontaneous formation of energetically stabilized monodisperse unilamellar vesicles whose radii are concentration independent and in contrast with previous experimental observations.
Publication date
In
  • Physical Review Letters 91, 158105 (10 October 2003).
LanguageEnglish
Peer reviewedYes
NPARC number12328825
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Record identifierda7a5c28-6b1e-41dd-8837-b4bde4f97e58
Record created2009-09-10
Record modified2023-05-16
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