Production of α2,6-sialylated IgG1 in CHO cells

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  1. National Research Council of Canada. Human Health Therapeutics
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SubjectB4GALT1; CHO cells; ECL, Erythrina Cristagalli lectin; GT, β1,4-galactosyltransferase 1; HILIC, hydrophilic interaction liquid chromatography; IgG1; LC-ESI-MS, liquid chromatography coupled to electrospray ionization mass spectrometry; MAL-II, Maackia Amurensis lectin II; N-glycosylation; PEI, polyethylenimine; SIAT1; SNA, Sambucus Nigra agglutinin; ST6, α2,6-sialyltransferase 1; TZM, trastuzumab (Herceptin®); cIEF, capillary zone electrophoresis isoelectric focusing; mAbs, monoclonal antibodies; sialylation; transfection; α2,3SA, α2,3-linked sialic acid; α2,6SA, α2,6-linked sialic acid
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PublisherTaylor & Francis Group
Peer reviewedYes
NRC numberNRC-HHT-53284
NPARC number21275405
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Record identifiere6369b2f-f442-4fe0-96b1-6e446ebe188f
Record created2015-07-08
Record modified2020-06-04
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