| Download | - View accepted manuscript: NIR spectroscopic imaging to map hemoglobin + myoglobin oxygenation, their concentration and optical pathlength across a beating pig heart during surgery (PDF, 1.7 MiB)
|
|---|
| DOI | Resolve DOI: https://doi.org/10.1002/jbio.201100031 |
|---|
| Author | Search for: Gussakovsky, Eugene1; Search for: Yang, Yanmin; Search for: Rendell, John1; Search for: Jilkina, Olga1; Search for: Kupriyanov, Valery1 |
|---|
| Affiliation | - National Research Council of Canada. NRC Institute for Biodiagnostics
|
|---|
| Format | Text, Article |
|---|
| Subject | NIR spectroscopic imaging; pig heart in vivo; hemoglobin +; myoglobin oxygenation and concentration; optical pathlength |
|---|
| Abstract | The purpose of this paper is to demonstrate that near-infrared (NIR) spectroscopic imaging can provide spatial distribution (maps) of the absolute concentration of hemoglobin + myoglobin, oxygen saturation parameter and optical pathlength, reporting on the biochemico-physiological status of a beating heart in vivo. The method is based on processing the NIR spectroscopic images employing a first-derivative approach. Blood-pressure-controlled gating compensated the effect of heart motion on the imaging. All the maps are available simultaneously and noninvasively at a spatial resolution in the submillimeter range and can be obtained in a couple of minutes. The equipment has no mechanical contact with the tissue, thereby leaving the heart unaffected during the measurement |
|---|
| Publication date | 2011-06-20 |
|---|
| In | |
|---|
| Language | English |
|---|
| Peer reviewed | Yes |
|---|
| NPARC number | 19726594 |
|---|
| Export citation | Export as RIS |
|---|
| Report a correction | Report a correction (opens in a new tab) |
|---|
| Record identifier | ec0d25a8-5bf8-4d63-a688-af9fc6355611 |
|---|
| Record created | 2012-05-11 |
|---|
| Record modified | 2020-06-04 |
|---|
