| DOI | Resolve DOI: https://doi.org/10.4236/jbise.2011.412093 |
|---|
| Author | Search for: Mao, Youxin1; Search for: Flueraru, Costel1; Search for: Chang, Shoude1 |
|---|
| Affiliation | - National Research Council of Canada. NRC Institute for Microstructural Sciences
|
|---|
| Format | Text, Article |
|---|
| Subject | optical coherence tomography; arterial plaque; medical and biological imaging; semiconductor optical amplifier |
|---|
| Abstract | Arterial plaque from a myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbit is visualized and characterized using a signal to noise ratio enhanced swept-source optical coherence tomography system with a quadrature interferometer (QSS-OCT). A semiconductor optical amplifier is used in the sample arm to amplify the weak signal scattered from arterial plague. Signal to noise ratio improvement are demonstrated in our QSS-OCT system. This finding results into an increase of the penetration depth possible in OCT images, from 1 mm to 2 mm. Preliminary results show that vulnerable plaque with fibrous cap, macrophage accumulations and calcification in the arterial tissue are measurable with our QSS-OCT system. |
|---|
| Publication date | 2011-12 |
|---|
| In | |
|---|
| Language | English |
|---|
| Peer reviewed | Yes |
|---|
| NPARC number | 21275142 |
|---|
| Export citation | Export as RIS |
|---|
| Report a correction | Report a correction (opens in a new tab) |
|---|
| Record identifier | f0b1ad9a-9896-43ed-b0f3-9f9459dcc82b |
|---|
| Record created | 2015-05-12 |
|---|
| Record modified | 2020-04-21 |
|---|
