Investigating a signature of temozolomide resistance in GBM cell lines using metabolomics

From National Research Council Canada

DOIResolve DOI: https://doi.org/10.1007/s11060-015-1899-6
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Affiliation
  1. National Research Council of Canada. Information and Communication Technologies
FormatText, Article
Subjectaconitic acid; adenosine; alanine; arginine; choline; citric acid; creatine; glucose; glutamic acid; glutamine; glutathione; glycerophosphate; histidine; inositol; isocitric acid; isoleucine; leucine; lomeguatrib; methionine; methylated DNA protein cysteine methyltransferase; phosphorylcholine; proline; serine; succinic acid; taurine; temozolomide; threonine; tryptophan; unindexed drug; valine; amino acid metabolism; antineoplastic activity; cancer cell line; cancer resistance; cell viability; citric acid cycle; concentration response; cytotoxicity; down regulation; drug sensitivity; enzyme inhibition; genetic transcription; glioblastoma; glioblastoma multiforme cell line; glycolysis; human cell; human tissue; metabolite; metabolomics; primary tumor; upregulation
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LanguageEnglish
Peer reviewedYes
NPARC number21276985
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Record created2015-11-10
Record modified2020-04-22
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