Label-free Biosensor Array Based on Silicon-on-Insulator Ring Resonators Addressed Using a WDM Approach

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Download	View accepted manuscript: Label-free Biosensor Array Based on Silicon-on-Insulator Ring Resonators Addressed Using a WDM Approach (PDF, 681 KiB)
DOI	Resolve DOI: https://doi.org/10.1364/OL.35.002771
Author	Search for: Xu, D. -X.¹; Search for: Vachon, M.¹; Search for: Densmore, A.¹; Search for: Ma, R.¹; Search for: Delâge, A.¹; Search for: Janz, S.¹; Search for: Lapointe, J.¹; Search for: Li, Y.²; Search for: Lopinski, G.²; Search for: Zhang, D.³; Search for: Liu, Q. Y.³; Search for: Cheben, P.¹; Search for: Schmid, J. H.¹
Affiliation	National Research Council of Canada. NRC Institute for Microstructural Sciences National Research Council of Canada. NRC Steacie Institute for Molecular Sciences National Research Council of Canada. NRC Institute for Biological Sciences
Format	Text, Article
Abstract	We report a silicon-on-insulator ring resonator biosensor array with one output port, using wavelength division multiplexing as the addressing scheme. With the use of on-chip referencing for environmental drift cancellation, simultaneous monitoring of multiplexed molecular bindings is demonstrated, with a resolution of 0:3 pg=mm2 (40 ag of total mass) for protein concentrations over 4 orders of magnitude down to 20 pM. Reactions are measured over time periods as long as 3 h with high stability.
Publication date	2010-08-01
In	Optics Letters 35, no. 16 (1 August 2010): 2771–2773.
Language	English
Peer reviewed	Yes
NRC publication	This is a non-NRC publication "Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.
NPARC number	17379833
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Record identifier	fa242fca-d0c8-46d3-84c2-e180e23e1134
Record created	2011-03-23
Record modified	2020-04-17

Date modified:: 2024-07-17