| Download | - View final version: Antisense oligonucleotides: absorption, distribution, metabolism, and excretion (PDF, 917 KiB)
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| DOI | Resolve DOI: https://doi.org/10.1080/17425255.2021.1992382 |
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| Author | Search for: Shadid, Mohammad; Search for: Badawi, Mohamed; Search for: Abulrob, Abedelnasser1 |
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| Affiliation | - National Research Council of Canada. Human Health Therapeutics
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| Funder | Search for: Sarepta Therapeutics Inc |
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| Format | Text, Article |
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| Subject | absorption; distribution; metabolism; excretion; antisense oligonucleotides; phosphorothioate; phosphorodiamidate morpholino oligomer; peptide-conjugated phosphorodiamidate morpholino oligomers |
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| Abstract | Antisense oligonucleotides (ASOs) have emerged as a promising novel drug modality that aims to address unmet medical needs. A record of six ASO drugs have been approved since 2016, and more candidates are in clinical development. ASOs are the most advanced class within the RNA-based therapeutics field. |
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| Publication date | 2021-11-02 |
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| Publisher | Taylor & Francis |
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| Licence | |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | fc78cb22-41a7-467c-a740-a20f5da1e7d5 |
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| Record created | 2022-09-16 |
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| Record modified | 2022-09-16 |
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