| Alternative title | Mock Yttrium-90 glass sphere standardization for nuclear medicine applications |
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| Download | - View final version: Mock Y-90 glass sphere standardization for nuclear medicine applications (PDF, 439 KiB)
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| DOI | Resolve DOI: https://doi.org/10.4224/40004093 |
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| Author | Search for: Galea, Raphael1ORCID identifier: https://orcid.org/0000-0003-1639-3788; Search for: Moore, Kimberly1 |
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| Affiliation | - National Research Council Canada. Metrology Research Centre
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| Format | Text, Technical Report |
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| Physical description | 8 p. |
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| Subject | glass microspheres; Y-90 microspheres; Yttrium-90; mock standard; nuclear medicine; radionuclide metrology |
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| Abstract | Reliable activity measurements of Yttrium-90 (Y-90) microspheres are critical for quantitative dosimetry and patient safety in liver radioembolization. Recent multicentre studies have identified systematic discrepancies between vendor-stated and independently measured Y-90 activities for both glass and resin microspheres, suggesting inconsistencies in calibration traceability across institutions. The NRC developed a mock glass microsphere standard designed to replicate the geometry and composition of clinical sources to address these metrological challenges. This paper summarizes the background of observed discrepancies, outlines the NRC approach for mock standard development and discusses implications for future standardization efforts. |
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| Date published | 2026-08-24 |
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| Publisher | National Research Council Canada |
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| Language | English |
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| Peer reviewed | No |
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| Identifier | PIRS-4571 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | fd51c064-074f-457a-82f0-10afd0f83161 |
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| Record created | 2026-08-19 |
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| Record modified | 2026-08-24 |
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