| DOI | Trouver le DOI : https://doi.org/10.1107/S0365110X60001308 |
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| Auteur | Rechercher : Kartha, G.1; Rechercher : Ahmed, F.R.1; Rechercher : Barnes, W.H.1 |
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| Affiliation | - Conseil national de recherches du Canada
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| Format | Texte, Article |
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| Résumé | The structure of the hydrochloride DL-alphaprodine has been determined by the isomorphous replacement method with the aid of data for the hydrobromide. Zero-level normal, and first-level generalized, projections along the three axes have been employed. The structure has been refined by three-dimensional Fourier and differential syntheses. The stereochemical configuration found for the alphaprodine molecule agrees with that of one of four possible isomers and confirms that proposed by Beckett and co-workers on conformational and other grounds. The piperidine ring has the chair form with the phenyl ring equatorial and the propionoxy chain axial; the methyl group on C(3) is trans to the phenyl ring on C(4). |
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| Date de publication | 1960 |
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| Dans | |
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| Note | Addendum to this paper available in Acta Crystallographica, Volume 14 (1), January 1961. (NRCC 6054). |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro du CNRC | NRCC 5621 |
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| Numéro NPARC | 21274957 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 06d0e467-7a5a-43c2-8b73-9adc5c347317 |
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| Enregistrement créé | 2015-05-04 |
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| Enregistrement modifié | 2020-03-12 |
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