| Téléchargement | - Voir le manuscrit accepté : Atomic Force Microscopy Force Mapping in the Study of Supported Lipid Bilayers (PDF, 762 Kio)
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| DOI | Trouver le DOI : https://doi.org/10.1021/la103927a |
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| Auteur | Rechercher : Li, James K.; Rechercher : Sullan, Ruby May A.1; Rechercher : Zou, Shan1 |
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| Affiliation | - Conseil national de recherches du Canada. Institut Steacie des sciences moléculaires du CNRC
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| Format | Texte, Article |
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| Résumé | Investigating the structural and mechanical properties of lipid bilayer membrane systems is vital in elucidating their biological function. One route to directly correlate the morphology of phase-segregatedmembranes with their indentation and rupture mechanics is the collection of atomic force microscopy (AFM) force maps. These force maps, while containing rich mechanical information, require lengthy processing time due to the large number of force curves needed to attain a high spatial resolution.Aforce curve analysis toolset was created to perform data extraction, calculation and reporting specifically in studying lipid membrane morphology and mechanical stability. The procedure was automated to allow for high-throughput processing of force maps with greatly reduced processing time. The resulting program was successfully used in systematically analyzing a number of supported lipid membrane systems in the investigation of their structure and nanomechanics. |
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| Date de publication | 2010-11-19 |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Publication du CNRC | Cette publication n’est pas du CNRCCe sont des publications qui ont été rédigées par un auteur du CNRC, mais avant que celui-ci soit employé du CNRC. |
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| Numéro NPARC | 17364204 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 172e1165-4ba7-413b-8b8d-e56c22df7601 |
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| Enregistrement créé | 2011-03-22 |
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| Enregistrement modifié | 2020-04-17 |
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