Sélection de la langue

Gouvernement du Canada / Government of Canada

Recherche

Dietary polyunsaturated fatty acids significantly affect laying hen lymphocyte proliferation and immunoglobulin G concentration in serum and egg yolk

Par Conseil national de recherches du Canada

DOITrouver le DOI : https://doi.org/10.4141/A00-013
AuteurRechercher : ; Rechercher : ; Rechercher : ; Rechercher :
FormatTexte, Article
Sujetlaying hens; n-3 polyunsaturated fatty acids; lymphocyte proliferation; immunoglobulin G; immunoglobulin Y
Résumé
Forty eight (48) Single Comb White Leghorn laying hens 24 wk of age were housed in cages and were fed wheat-soybean meal based diets with added oils [sunflower oil (SO), animal oil (AO), linseed oil (LO), or fish oil (FO)] at 5%. After 5 wk on experimental diets, spleen lymphocytes and peripheral blood lymphocytes were obtained from six birds and assayed for polyclonal mitogen Con A-induced proliferative response and the proportions of lymphocyte subsets. The IgG concentration in serum and egg yolk was also measured. Feeding LO and FO resulted in an increase in longer-chain n-3 polyunsaturated fatty acids (PUFA) (C20:5n-3, C22:5n-3, and C22:6n-3) with a concurrent decrease of C20: 4n-6 in spleen lymphocytes (P < 0.05). The highest enrichments of the longer-chain n-3 PUFA were achieved by feeding FO. The content of C20: 4n-6 was higher (P < 0.05) in the lymphocytes of hens fed AO and SO. Subsequently, Con A-stimulated proliferation of spleen and peripheral blood lymphocytes were significantly suppressed (P < 0.05) in the chicks fed high n-3 PUFA diets (LO and FO). The LO diet increased (P < 0.05) the IgG concentration in laying hen serum. The SO diet reduced (P < 0.05) IgY content in egg yolk. Dietary fatty acids did not affect (P > 0.05) the proportions of lymphocyte subsets in spleen and blood lymphocytes. It is indicated that the ratio of n-6 to n3 PUFA plays a major role in modulating cell-mediated and humoral immune responses of laying hens, and various n-3 fatty acids possess different potencies of immunomodulation. Key words: Laying hens, n-3 polyunsaturated fatty acids, lymphocyte proliferation, immunoglobulin G, immunoglobulin Y
Date de publication
Dans
  • Canadian Journal of Animal Science 80, nº 4 (2000) : 597–604.
Langueanglais
Publications évaluées par des pairsOui
Publication du CNRC
Cette publication n’est pas du CNRC

Ce sont des publications qui ont été rédigées par un auteur du CNRC, mais avant que celui-ci soit employé du CNRC.

Numéro NPARC21273949
Exporter la noticeExporter en format RIS
Signaler une correctionSignaler une correction (s'ouvre dans un nouvel onglet)
Identificateur de l’enregistrement1eae3653-b22f-4a5c-9fb5-8228b528356c
Enregistrement créé2015-02-04
Enregistrement modifié2020-03-26
Date de modification :