| Téléchargement | - Voir le manuscrit accepté : Collagen morphology and texture analysis : from statistics to classification (PDF, 1.8 Mio)
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| DOI | Trouver le DOI : https://doi.org/10.1038/srep02190 |
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| Auteur | Rechercher : Mostaço-Guidolin, Leila B.1; Rechercher : Ko, Alex C.-T.1; Rechercher : Wang, Fei1; Rechercher : Xiang, Bo1; Rechercher : Hewko, Mark1; Rechercher : Tian, Ganghong1; Rechercher : Major, Arkady; Rechercher : Shiomi, Masashi; Rechercher : Sowa, Michael G.1 |
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| Affiliation | - Conseil national de recherches du Canada. Dispositifs médicaux
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| Format | Texte, Article |
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| Sujet | SHG, collagen, classification, texture, gray level co-occurance matrix, multiphoton microscopy |
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| Résumé | In this study we present an image analysis methodology capable of quantifying morphological changes in tissue collagen fibril organization caused by pathological conditions. Texture analysis based on first-order statistics (FOS) and second-order statistics such as gray level co-occurrence matrix (GLCM) was explored to extract second-harmonic generation (SHG) image features that are associated with the structural and biochemical changes of tissue collagen networks. Based on these extracted quantitative parameters, multi-group classification of SHG images was performed. With combined FOS and GLCM texture values, we achieved reliable classification of SHG collagen images acquired from atherosclerosis arteries with >90% accuracy, sensitivity and specificity. The proposed methodology can be applied to a wide range of conditions involving collagen re-modeling, such as in skin disorders, different types of fibrosis and muscular-skeletal diseases affecting ligaments and cartilage. |
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| Date de publication | 2013-07-12 |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro NPARC | 21268602 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 58e777b9-73a7-484e-918d-49d5e07f0b9b |
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| Enregistrement créé | 2013-10-25 |
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| Enregistrement modifié | 2020-06-04 |
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