| Auteur | Rechercher : Cox, A.; Rechercher : Masoud, H.; Rechercher : Thibault, P.; Rechercher : Brisson, J.; Rechercher : Van Der, Zwan; Rechercher : Perry, Malcolm; Rechercher : Richards, J. |
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| Format | Texte, Article |
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| Sujet | Canada; carbohydrate conformation; classification; core region; Haemophilus influenzae; isolation & purification; Lipopolysaccharides; LPS; magnetic resonance spectroscopy; mass spectrometry; methylation; molecular sequence data; NMR; NMR spectroscopy; oligosaccharides; phosphorylcholine; region; residues; series; spectrometry, mass, electrospray ionization; strain; structural analysis; structure; trisaccharide |
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| Résumé | The structure of the core region of the lipopolysaccharide (LPS) from the nontypable Haemophilus influenzae strain SB 33 was elucidated. The LPS was subjected to a variety of degradative procedures. The structures of the derived oligosaccharide products were established by monosaccharide and methylation analyses, NMR spectroscopy and mass spectrometry. These analyses revealed a series of related phosphocholine (PCho) containing structures differing in the number of hexose residues. The results pointed to each species containing a conserved phosphoethanolamine (PEtn) substituted heptose-containing trisaccharide inner-core moiety. The major LPS glycoforms were identified as 2-Hex, 3-Hex and 4-Hex species according to the number of hexose residues present |
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| Date de publication | 2001-10 |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro du CNRC | COX2001 |
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| Numéro NPARC | 9379733 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 5b00f96f-e71a-43e4-a944-d0d5055310ca |
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| Enregistrement créé | 2009-07-10 |
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| Enregistrement modifié | 2020-03-27 |
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