Shedding light on cobalamin photodegradation in the ocean

Par Conseil national de recherches du Canada

Téléchargement	Voir la version finale : Shedding light on cobalamin photodegradation in the ocean (PDF, 1.3 Mio)
DOI	Trouver le DOI : https://doi.org/10.1002/lol2.10371
Auteur	Rechercher : Bannon, Catherine C.Identifiant ORCID : https://orcid.org/0000-0002-8581-1069; Rechercher : Mudge, Elizabeth M.¹Identifiant ORCID : https://orcid.org/0000-0003-2266-5639; Rechercher : Bertrand, Erin M.Identifiant ORCID : https://orcid.org/0000-0002-5950-6810
Affiliation	Conseil national de recherches du Canada. Centre de recherche en métrologie
Bailleur de fonds	Rechercher : Canada Research Chairs; Rechercher : Natural Sciences and Engineering Research Council of Canada; Rechercher : Simons Foundation
Format	Texte, Article
Sujet	vitamin ecology; marine metabolites; B₁₂ intermediates
Résumé	Cobalamin, vitamin B₁₂, is an important micronutrient that has been investigated for decades in the marine context because it is required for phytoplankton growth. The biologically active forms (Me-B₁₂, Ado-B₁₂) and the synthetic form (CN-B₁₂) quickly convert to OH-B₁₂ after light exposure in various aqueous solutions, but puzzlingly have been frequently reported to dominate dissolved cobalamin pools in the sunlit ocean. Here, we document photodegradation timescales for these cobalamin forms in natural seawater using targeted mass spectrometry, providing quantitative evidence that OH-B₁₂ is expected to be the dominant dissolved form in irradiated seawater. Then, through high-resolution mass spectrometry, we identify four photodegradation products of OH-B₁₂ which represent potential building blocks microbes could salvage and remodel to satisfy cellular cobalamin requirements. Taken together, these results clarify the impact of light on marine cobalamin dynamics, laying a foundation for a more quantitative understanding of the role of cobalamin in microbial communities and biogeochemical cycles.
Date de publication	2023-12-14
Maison d’édition	Wiley Association for the Sciences of Limnology and Oceanography
Licence	Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/deed.fr
Dans	Limnology and Oceanography Letters (14 décembre 2023).
Données connexes	Bannon, Catherine, Elizabeth Mudge, et Erin Bertrand. « Data From: Shedding light on cobalamin photodegradation in the ocean ». Dryad, 28 novembre 2023. https://doi.org/10.5061/DRYAD.D51C5B087.
Langue	anglais
Publications évaluées par des pairs	Oui
Exporter la notice	Exporter en format RIS
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Identificateur de l’enregistrement	7c92ddfd-5484-412a-9235-4311ebd0ec63
Enregistrement créé	2024-01-19
Enregistrement modifié	2024-01-19

Date de modification :: 2024-06-29