| DOI | Trouver le DOI : https://doi.org/10.1371/journal.pone.0058130 |
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| Auteur | Rechercher : Mazerolle, E.L.1; Rechercher : Gawryluk, J.R.1; Rechercher : Dillen, K.N.H.1; Rechercher : Patterson, S.A.1; Rechercher : Feindel, K.W.1; Rechercher : Beyea, S.D.1; Rechercher : Stevens, M.T.R.1; Rechercher : Newman, A.J.; Rechercher : Schmidt, M.H.; Rechercher : D'Arcy, R.C.N.1 |
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| Affiliation | - Conseil national de recherches du Canada. Institut du biodiagnostic du CNRC
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| Format | Texte, Article |
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| Sujet | adult; female; field strength; functional magnetic resonance imaging; gray matter; human experiment; image analysis; male; motor performance; normal human; radiological parameters; sensorimotor cortex; signal noise ratio; task performance; white matter |
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| Résumé | Functional magnetic resonance imaging (fMRI) activation in white matter is controversial. Given that many of the studies that report fMRI activation in white matter used high field MRI systems, we investigated the field strength dependence of sensitivity to white matter fMRI activation. In addition, we evaluated the temporal signal to noise ratio (tSNR) of the different tissue types as a function of field strength. Data were acquired during a motor task (finger tapping) at 1.5 T and 4 T. Group and individual level activation results were considered in both the sensorimotor cortex and the posterior limb of the internal capsule. We found that sensitivity increases associated with field strength were greater for white matter than gray matter. The analysis of tSNR suggested that white matter might be less susceptible to increases in physiological noise related to increased field strength. We therefore conclude that high field MRI may be particularly advantageous for fMRI studies aimed at investigating activation in both gray and white matter. © 2013 Mazerolle et al. |
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| Date de publication | 2013 |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro NPARC | 21269637 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 94693025-f576-4938-8fda-31d7f2f6b6fb |
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| Enregistrement créé | 2013-12-13 |
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| Enregistrement modifié | 2021-09-17 |
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