Autre titre | Primary standardization and half-life determination of 225 Ac at NRC |
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Téléchargement | - Sera disponible ici le 8 novembre 2025
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DOI | Trouver le DOI : https://doi.org/10.1016/j.apradiso.2023.111105 |
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Auteur | Rechercher : Galea, R.1Identifiant ORCID : https://orcid.org/0000-0003-1639-3788; Rechercher : Moore, K.1 |
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Affiliation | - Conseil national de recherches du Canada. Centre de recherche en métrologie
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Bailleur de fonds | Rechercher : Canadian Nuclear Laboratories |
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Format | Texte, Article |
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Sujet | ²²⁵Ac; targeted alpha therapy; half-life |
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Résumé | A solution of ²²⁵ Ac was standardized by NRC using the triple-to-double coincidence ratio (TDCR) method. The counting efficiencies were calculated assuming a counting efficiency of 100% for alpha decays and those calculated using the MICELLE2 Monte Carlo code for beta decays and was approximately 500% for the NRC TDCR system. The relative uncertainty for the activity concentration was determined to be 0.25%. This agreed with measurements performed using gamma spectroscopy and a predicted calibration factor for the Vinten 671 ionization chamber as calculated using an EGSnrc model, implementing radioactive decay. Finally, the half-life of ²²⁵ Ac was determined from long-term measurements using ionization chambers and liquid scintillation counting. The NRC measured half-life for ²²⁵ Ac was found to be 9.914(4) days and is consistent within an expanded uncertainty coverage of k = 2 with the most recent (Kossert et al., 2020; Pommé et al., 2012) measurements of this decay parameter. |
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Date de publication | 2023-11-08 |
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Maison d’édition | Elsevier |
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Dans | |
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Langue | anglais |
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Publications évaluées par des pairs | Oui |
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Exporter la notice | Exporter en format RIS |
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Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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Identificateur de l’enregistrement | 9aa29a95-2011-4861-a3d9-706cc9649d1f |
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Enregistrement créé | 2024-01-08 |
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Enregistrement modifié | 2024-01-10 |
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