| DOI | Trouver le DOI : https://doi.org/10.1021/np300520w |
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| Auteur | Rechercher : Berrué, Fabrice; Rechercher : Mcculloch, Malcolm W. B.; Rechercher : Boland, Patricia; Rechercher : Hart, Saskia; Rechercher : Harper, Mary Kay; Rechercher : Johnston, James1; Rechercher : Kerr, Russell |
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| Affiliation | - Conseil national de recherches du Canada. Développement des cultures et des ressources aquatiques
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| Format | Texte, Article |
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| Résumé | Four new steroidal glycosides, acanthifoliosides G–J (1–4), were isolated as minor constituents from the Caribbean marine sponge Pandaros acanthifolium. These metabolites are characterized by a highly oxygenated D ring and the presence of a disaccharide rhamnose-glucose residue and a rhamnose at positions C-3 and C-15, respectively. Their structures were established on the basis of extensive interpretation of 1D and 2D NMR data and HRESIMS analyses. The absolute configurations of the glucose and rhamnose sugars were determined by preparing aldose o-tolylthiocarbamate derivatives and comparison to authentic standards by LC/HRESIMS. Acanthifolioside G (1) exhibited antioxidant and cytoprotective activities. |
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| Date de publication | 2012-12-17 |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro NPARC | 21268909 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | a210ab6b-656e-414d-a732-e732b4083cd6 |
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| Enregistrement créé | 2013-11-25 |
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| Enregistrement modifié | 2020-04-21 |
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